Clinical Trials

A review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials

Background/Aims - Stepped-wedge cluster randomized trials tend to require fewer clusters than standard parallel-arm designs due to the switches between control and intervention conditions, but there are no recommendations for the minimum number of …

Adherence to key recommendations for design and analysis of stepped-wedge cluster randomized trials - A review of trials published 2016–2022

Background/Aims - The stepped-wedge cluster randomized trial (SW-CRT), in which clusters are randomized to a time at which they will transition to the intervention condition – rather than a trial arm – is a relatively new design. SW-CRTs have …